HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-7-(4-fluoro-phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one → 2-Amino-7-thien-2-yl-4-methyl-7,8-dihydro-6H-quinazolin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-7-(4-fluoro-phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one | HCID 17221208 | — |
| Reactant | 2-Acetyl-5-thien-2-yl-cyclohexane-1,3-dione | HCID 52950249 | — |
| Product | 2-Amino-7-thien-2-yl-4-methyl-7,8-dihydro-6H-quinazolin-5-one | HCID 17221211 | — |
Reaction Steps
The title compound was prepared from 2-acetyl-5-thien-2-yl-cyclohexane-1,3-dione (430 mg, 1.82 mmol), from stage 1, following the procedure describing the synthesis of 2-amino-7-(4-fluoro-phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08592430B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-cd1f57a462ed4f5ab3ccc7175d9d4059 |
| Source note | uspto-grants-2013_11 |