HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-7-(2-bromo-phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one → 2-Amino-7-[2-(1H-indol-7-yl)-phenyl]-4-methyl-7,8-dihydro-6H-quinazolin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-7-(2-bromo-phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one | HCID 11979145 | — |
| Reactant | 2-amino-7-biphenyl-2-yl-4-methyl-7,8-dihydro-6H-quinazolin-5-one | HCID 58269344 | — |
| Product | 2-Amino-7-[2-(1H-indol-7-yl)-phenyl]-4-methyl-7,8-dihydro-6H-quinazolin-5-one | HCID 58269383 | — |
Reaction Steps
The title compound was prepared from 2-amino-7-(2-bromo-phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one (example 3/i stage 2/3), following the procedure describing the synthesis of 2-amino-7-biphenyl-2-yl-4-methyl-7,8-dihydro-6H-quinazolin-5-one (example 5/a stage 1) using 7-boronic acid-1H-indole instead of phenyl-boronic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08592430B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-ff77f81f0d1b498fa43fffeb4b149a70 |
| Source note | uspto-grants-2013_11 |