HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → 1-(2,3-Dichloro-4-fluoro-5-methylphenyl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Reactant | 3,4-Dichloro-2-fluorotoluene | HCID 59370502 | — |
| Product | 1-(2,3-Dichloro-4-fluoro-5-methylphenyl)ethanone | HCID 59370495 | — |
Reaction Steps
Using 1,2-dichloro-3-fluoro-4-methylbenzene (12.0 g), anhydrous aluminum chloride (17.87 g) and acetyl chloride (5.26 g), the title compound was obtained as a pale-yellow oil (yield: 5.46 g) by an operation similar to that in Reference Example 9.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08592452B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-a7bd01da43c74d5c98fdd01a6e9a26db |
| Source note | uspto-grants-2013_11 |