Propargyl alcohol → 5,11-Dihydro-11-[[(2-propynyl)oxy]carbonyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
Reaction equation
[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH2:6]([C:7]#[CH:8])[OH:9].[CH3:29][CH2:30][CH2:31][CH2:32][CH2:33][CH3:34].[Cl:10][C:11](=[O:12])[N:13]1[c:14]2[c:15]([cH:25][cH:26][cH:27][n:28]2)[NH:16][C:17](=[O:24])[c:18]2[c:19]1[cH:20][cH:21][cH:22][cH:23]2.[O:35]1[CH2:36][CH2:37][CH2:38][CH2:39]1>>[CH2:6]([C:7]#[CH:8])[O:9][C:11](=[O:12])[N:13]1[c:14]2[c:15]([cH:25][cH:26][cH:27][n:28]2)[NH:16][C:17](=[O:24])[c:18]2[c:19]1[cH:20][cH:21][cH:22][cH:23]2Participants
6
Sources & evidence
- ORD record
- ord-f7a053be766b4fb3b581bee2273bb407
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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