Dichloromethane → 4-chloro-8-(2,6-difluorophenyl)-2-(4-methyl-1,4'-bipiperidin-1'-yl)pyrido[2,3-d]pyrimidin-7(8H)-one
Reaction equation
[CH3:24][CH:25]1[CH2:26][CH2:27][N:28]([CH:31]2[CH2:32][CH2:33][NH:34][CH2:35][CH2:36]2)[CH2:29][CH2:30]1.[CH3:37][CH2:38][N:39]([CH2:40][CH3:41])[CH2:42][CH3:43].[Cl:1][c:2]1[c:3]2[c:4]([n:5][c:6]([S:8]([CH3:9])=[O:10])[n:7]1)[n:11](-[c:16]1[c:17]([F:23])[cH:18][cH:19][cH:20][c:21]1[F:22])[c:12](=[O:15])[cH:13][cH:14]2.[Cl:44][CH2:45][Cl:46]>>[Cl:1][c:2]1[c:3]2[c:4]([n:5][c:6]([N:34]3[CH2:33][CH2:32][CH:31]([N:28]4[CH2:27][CH2:26][CH:25]([CH3:24])[CH2:30][CH2:29]4)[CH2:36][CH2:35]3)[n:7]1)[n:11](-[c:16]1[c:17]([F:23])[cH:18][cH:19][cH:20][c:21]1[F:22])[c:12](=[O:15])[cH:13][cH:14]2Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-e824133a4a0c4bbdbd605d2aba751d75
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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