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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2047340Generated: October 27, 2026

2-(Diethylamino)-6-methylisonicotinic acid → Diethyl-{6-methyl-4-[3-(4-propoxy-phenyl)-[1,2,4]oxadiazol-5-yl]-pyridin-2-yl}-amine

https://huagongshe.com/reaction/2047340

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Diethylamino)-6-methylisonicotinic acidHCID 58418055—
ReactantN-Hydroxy-4-propoxy-benzamidineHCID 178458440—
ProductDiethyl-{6-methyl-4-[3-(4-propoxy-phenyl)-[1,2,4]oxadiazol-5-yl]-pyridin-2-yl}-amineHCID 68578166—

Reaction Steps

The title compound is prepared in analogy to Example 5 starting from N-hydroxy-4-propoxy-benzamidine and 2-diethylamino-6-methyl-isonicotinic acid; LC-MS: tR=1.41*min; [M+1]+=367.09.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08592460B2
Source datasetuspto-grants-2013_11
ORD IDord-b700d9bb8bdf4c3594647ade2f6f0772
Source noteuspto-grants-2013_11