反应详情

A solution of 4-[3-(2-amino-phenylcarbamoyl)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester (1.20 g, 3.03 mmol) in acetic acid (12 mL) was heated overnight at 55° C., then the solvent was removed under reduced pressure. The solid obtained was triturated with Et2O to afford the title compound as a white solid (0.90 g, 79%) without further purification.

1. customthe solvent was removed under reduced pressure
2. customThe solid obtained
3. customwas triturated with Et2O