HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazin-1-yl-pyrrolidin-1-yl-methanone → HCID 68670755, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazin-1-yl-pyrrolidin-1-yl-methanone | HCID 2760443 | — |
| Reactant | 2-(5-Bromo-2-fluoro-phenyl)-1-methyl-1H-benzoimidazole | HCID 59568190 | — |
| Product | HCID 68670755 | HCID 68670755 | 44% |
Reaction Steps
The same procedure described in step c method J was followed but starting from 2-(5-bromo-2-fluoro-phenyl)-1-methyl-1H-benzoimidazole and piperazin-1-yl-pyrrolidin-1-yl-methanone. The crude reaction mixture was purified by preparative HPLC to afford 0.06 g of the title compound (44%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08592463B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-1deec26b9d6c425fa05ec02448894dcf |
| Source note | uspto-grants-2013_11 |