HCID 86655961, compound → (Z)-Benzaldehyde oxime

HRID 2047576Notes

Reaction equation

HRID 2047576 reaction equation
CS(Cl)(=O)=O.CN1CCCC1=O.[CH:13](=[N:20][OH:21])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.CN1CCCC1=O>C(#N)C1C=CC=CC=1>[CH:13](=[N:20][OH:21])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

4

Reactant 2

HCID 86655961HCID 86655961, compoundHCID 86655962HCID 86655962, compound

Product 1

HCID 12143(Z)-Benzaldehyde oxime

Reagents, catalysts & solvents 1

HCID 7505BenzonitrileSolvent

Procedure

A 1.5 mol/L methanesulfonyl chloride/N-methylpyrrolidone solution was sent as a first fluid from the center at a ratio of supply pressure/back pressure of 0.10 MPa/0.03 MPa, a rotation speed of 1000 rpm, and a sending temperature of 25° C., and a 1.0 mol/L benzaldoxime/N-methylpyrrolidone solution was introduced as a second fluid into a space between the processing surfaces at 20 mL/min. The first fluid and the second fluid were mixed in a thin film fluid, and then a solution obtained after processing was discharged from the space between the processing surfaces at 44 mL/min. As a result of HPLC analysis, substantially complete conversion of benzaldoxime to benzonitrile was observed.

Workup

  1. additionThe first fluid and the second fluid were mixed in a thin film fluid
  2. customa solution obtained after processing

Sources & evidence

ORD record
ord-e3c1499d9c4b401ab69cd7bed1a52286
Source dataset
uspto-grants-2013_11
Patent number
US08592498B2

Reaction notes

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