HCID 85722021, compound → Acetanilide

HRID 2047577Notes

Reaction equation

HRID 2047577 reaction equation
CS(Cl)(=O)=[O:3].[N:6]1C=CC=[CH:8][CH:7]=1.C(=NO)([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)C.N1C=CC=CC=1>>[C:7]([NH:6][C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)(=[O:3])[CH3:8]

Participants

3

Reactant 2

HCID 85722021HCID 85722021, compoundHCID 86655963HCID 86655963, compound

Product 1

HCID 904Acetanilide

Procedure

A 0.15 mol/L methanesulfonyl chloride/pyridine solution was sent as a first fluid from the center at a ratio of supply pressure/back pressure of 0.15 MPa/0.07 MPa, a rotation speed of 500 rpm, and a sending temperature of 25° C., and a 0.1 mol/L acetophenone oxime/pyridine solution was introduced as a second fluid into a space between the processing surfaces at 30 mL/min. The first fluid and the second fluid were mixed in a thin film fluid, and then a solution obtained after processing was discharged from the space between the processing surfaces at 58 mL/min. As a result of HPLC analysis, substantially complete conversion to acetanilide was observed.

Workup

  1. additionThe first fluid and the second fluid were mixed in a thin film fluid
  2. customa solution obtained after processing

Sources & evidence

ORD record
ord-0092319d7c29477a899c93d33e6423dc
Source dataset
uspto-grants-2013_11
Patent number
US08592498B2

Reaction notes

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