Phenethylamine → HCID 67182730, compound

HRID 2047613Notes

Reaction equation

HRID 2047613 reaction equation
[CH3:1]OC1C=CC=CC=1CCN.C(N)CC1C=CC=CC=1.[CH3:21][S:22][C:23]1[NH:28][C:27](=[O:29])[N:26]=[C:25]([C:30]2[CH:35]=[CH:34][N:33]=[CH:32][CH:31]=2)[N:24]=1>>[CH3:1][N:28]1[C:23]([S:22][CH3:21])=[N:24][C:25]([C:30]2[CH:35]=[CH:34][N:33]=[CH:32][CH:31]=2)=[N:26][C:27]1=[O:29]

Participants

4

Reactant 3

HCID 1001PhenethylamineHCID 748962-MethoxyphenethylamineHCID 178503394HCID 178503394, compound

Product 1

HCID 67182730HCID 67182730, compound

Procedure

By analogy with the method described in example 1 (step 1.2), using 2-(2-Methoxy-phenyl)-ethylamine (commercially available) in place of phenethylamine and 6-Methylsulfanyl-4-pyridin-4-yl-1H-[1,3,5]triazin-2-one (synthesis as described in U.S. Pat. No. 4,406,897) in place of 1-Methyl-6-methylsulfanyl-4-pyridin-4-yl-1H-[1,3,5]triazin-2-one, to afford the product which was transformed into the hyrdochloride salt in the usual manner to give 0.11 g (51%) of a white solid.

Workup

  1. customsynthesis

Sources & evidence

ORD record
ord-cfc05de30e90447c838ab6fcbbe239f1
Source dataset
uspto-grants-2013_11
Patent number
US08592580B2

Reaction notes

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