Ethyl Acetoacetate → HCID 66746843, compound

HRID 2047725Notes

Reaction equation

[NH2:1][C:2]1[C:3]([C:10]#[N:11])=[N:4][C:5]([O:8][CH3:9])=[CH:6][CH:7]=1.O=[C:13]([CH3:20])[CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16]>>[CH2:18]([O:17][C:15]([C:14]1[C:13]([CH3:20])=[N:1][C:2]2[C:3]([C:10]=1[NH2:11])=[N:4][C:5]([O:8][CH3:9])=[CH:6][CH:7]=2)=[O:16])[CH3:19]

Participants

Reactant 2

HCID 8868Ethyl Acetoacetate

HCID 55253214HCID 55253214, compound

Product 1

HCID 66746843HCID 66746843, compound

Procedure

Prepared as in Example 2a from 3-amino-6-methoxypicolinonitrile (Example 11b) and ethyl 3-oxobutanoate as an off white solid (45%). MS 262 (MH+).

Sources & evidence

ORD record: ord-e9b3b2550d8f42aba51a9752afe45f06
Source dataset: uspto-grants-2013_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08592592B2

Reaction notes

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