HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine → Ethyl 4-amino-5-(3-((5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)amino)-2,2-dimethyl-3-oxopropoxy)-2-methylquinoline-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine | HCID 38899 | — |
| Reactant | 3-((4-Amino-3-(ethoxycarbonyl)-2-methylquinolin-5-yl)oxy)-2,2-dimethylpropanoic acid | HCID 66746878 | — |
| Product | Ethyl 4-amino-5-(3-((5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)amino)-2,2-dimethyl-3-oxopropoxy)-2-methylquinoline-3-carboxylate | HCID 66746982 | — |
Reaction Steps
Prepared as in Example 24a from 3-((4-amino-3-(ethoxycarbonyl)-2-methylquinolin-5-yl)oxy)-2,2-dimethylpropanoic acid (Example 47b) and 5-methoxy-1,2,3,4-tetrahydronaphthalen-1-amine as a brown solid (40%). MS 506 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08592592B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-7025330e9bf848a4b38dd84bdcc93499 |
| Source note | uspto-grants-2013_11 |