Ethyl Acetoacetate → HCID 66747338, compound

HRID 2047856Notes

Reaction equation

HRID 2047856 reaction equation
[NH2:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([CH:10]2[CH2:12][CH2:11]2)[C:3]=1[C:4]#[N:5].O=[C:14]([CH3:21])[CH2:15][C:16]([O:18][CH2:19][CH3:20])=[O:17]>>[CH2:19]([O:18][C:16]([C:15]1[C:14]([CH3:21])=[N:1][C:2]2[C:3]([C:4]=1[NH2:5])=[C:6]([CH:10]1[CH2:11][CH2:12]1)[CH:7]=[CH:8][CH:9]=2)=[O:17])[CH3:20]

Participants

3

Reactant 2

HCID 8868Ethyl AcetoacetateHCID 667472522-Amino-6-cyclopropylbenzonitrile

Product 1

HCID 66747338HCID 66747338, compound

Procedure

Prepared as in Example 2a from 2-amino-6-cyclopropylbenzonitrile (Tachdjian, C. et al. PCT Int. Appl. 2008, WO 2008154221) and ethyl 3-oxobutanoate as a pale yellow solid (80%). MS 271 (MH+).

Sources & evidence

ORD record
ord-fee854d3e8d048b3a5414521d871cbb5
Source dataset
uspto-grants-2013_11
Patent number
US08592592B2

Reaction notes

Loading…