4-Methoxybenzylamine → HCID 66746021, compound

HRID 2047865Notes

Reaction equation

HRID 2047865 reaction equation
[NH2:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][C:10]=2[O:12][CH2:13][C:14]([CH3:19])([CH3:18])[C:15]([OH:17])=O)[N:5]=[C:4]([CH3:20])[C:3]=1[C:21]([O:23][CH2:24][CH3:25])=[O:22].[CH3:26][O:27][C:28]1[CH:33]=[CH:32][C:31]([CH2:34][NH2:35])=[CH:30][CH:29]=1>>[CH2:24]([O:23][C:21]([C:3]1[C:4]([CH3:20])=[N:5][C:6]2[C:11]([C:2]=1[NH2:1])=[C:10]([O:12][CH2:13][C:14]([CH3:18])([CH3:19])[C:15]([NH:35][CH2:34][C:31]1[CH:32]=[CH:33][C:28]([O:27][CH3:26])=[CH:29][CH:30]=1)=[O:17])[CH:9]=[CH:8][CH:7]=2)=[O:22])[CH3:25]

Participants

3

Reactant 2

HCID 754524-MethoxybenzylamineHCID 667468783-((4-Amino-3-(ethoxycarbonyl)-2-methylquinolin-5-yl)oxy)-2,2-dimethylpropanoic acid

Product 1

HCID 66746021HCID 66746021, compound

Procedure

Prepared as in Example 24a from 3-((4-amino-3-(ethoxycarbonyl)-2-methylquinolin-5-yl)oxy)-2,2-dimethylpropanoic acid (Example 47b) and (4-methoxyphenyl)methanamine as a yellow solid (100%). MS 466 (MH+).

Sources & evidence

ORD record
ord-a0262a04565e4e7ebc897af6bba6600d
Source dataset
uspto-grants-2013_11
Patent number
US08592592B2

Reaction notes

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