Ethyl Acetoacetate → HCID 66746511, compound

HRID 2047869Notes

Reaction equation

HRID 2047869 reaction equation
C([O:4][CH2:5][C:6]([CH3:19])([CH3:18])[CH2:7][O:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([NH2:15])[C:10]=1[C:16]#[N:17])(=O)C.O=[C:21]([CH3:28])[CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24]>>[CH2:26]([O:25][C:23]([C:22]1[C:21]([CH3:28])=[N:15][C:11]2[C:10]([C:16]=1[NH2:17])=[C:9]([O:8][CH2:7][C:6]([CH3:18])([CH3:19])[CH2:5][OH:4])[CH:14]=[CH:13][CH:12]=2)=[O:24])[CH3:27]

Participants

3

Reactant 2

HCID 8868Ethyl AcetoacetateHCID 66747072HCID 66747072, compound

Product 1

HCID 66746511HCID 66746511, compound

Procedure

Prepared as in Example 2a from 3-(3-amino-2-cyanophenoxy)-2,2-dimethylpropyl acetate (Tachdjian, C. et al. PCT Int. Appl. 2008, WO 2008154221) and ethyl 3-oxobutanoate as a pale yellow solid (26%). MS 333 (MH+).

Sources & evidence

ORD record
ord-a7f4ac222ffd4389ac77bcdc90b1f6a0
Source dataset
uspto-grants-2013_11
Patent number
US08592592B2

Reaction notes

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