HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → 1H-pyrrole-2-carbohydrazonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | Pyrrole-2-carbonitrile | HCID 138277 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1H-pyrrole-2-carbohydrazonamide | HCID 136387248 | — |
Reaction Steps
A solution of 1H-pyrrole-2-carbonitrile 10 g (108 mM) and sodium methoxide (1 eq) in ethanol (20 ml) and stirred for 10 min. Hydrazine hydrate (3 eq.) is then added and resulting reaction mixture is stirred at room temperature for 18 hrs. Reaction mass is then diluted with water, extracted with ethyl acetate, dried over anhydrous sodium sulphate and concentrated under vacuum to yield desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08592591B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-b2f4fdbed86e461184fdb9e306592e34 |
| Source note | uspto-grants-2013_11 |