Ethanone, 1-(3,4-dichlorophenyl)- → HCID 86736902, compound

HRID 2049032Notes

Reaction equation

HRID 2049032 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:9](=O)[CH3:10])[CH:5]=[CH:6][C:7]=1[Cl:8].[NH2:12][O:13][CH2:14][C:15]([NH2:17])=[O:16]>C(O)C>[CH3:10][C:9](=[N:12][O:13][CH2:14][C:15]([NH2:17])=[O:16])[C:4]1[CH:5]=[CH:6][C:7]([Cl:8])=[C:2]([Cl:1])[CH:3]=1

Participants

4

Reactant 2

HCID 75841Ethanone, 1-(3,4-dichlorophenyl)-HCID 139561842-(Aminooxy)acetamide

Product 1

HCID 86736902HCID 86736902, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 5.0 g of 3', 4'-dichloroacetophenone in 50 ml of 90% ethanol was mixed with 2.4 g of aminooxyacetamide and subsequently boiled. The solvent was removed in a vacuum and the residue was extracted with chloroform. The chloroform solution was washed thrice with water, dried over anhydrous sodium sulfate and subsequently concentrated by evaporation in a vacuum. After the addition of ether and petroleum ether the superscribed substance crystallized out from the concentrate. Melting point 111° C.-111.5° C.

Workup

  1. customThe solvent was removed in a vacuum
  2. extractionthe residue was extracted with chloroform
  3. washThe chloroform solution was washed thrice with water
  4. dry with materialdried over anhydrous sodium sulfate
  5. concentrationsubsequently concentrated by evaporation in a vacuum
  6. additionAfter the addition of ether and petroleum ether the superscribed substance
  7. customcrystallized out from the concentrate

Sources & evidence

ORD record
ord-e7004c3621d54bd08d44945826de049b
Source dataset
uspto-grants-1980_04
Patent number
US04196216

Reaction notes

Loading…