2-Acetylthiophene → HCID 20345883, compound

Participants

Reaction Steps

756 g (6 moles) of acetyl-thiophene and 613 g (8.4 moles) of n-butylamine are azeotropically dehydrated in 2598 g of toluene in the presence of 15 g of formic acid. It is then concentrated under vacuum and mixtures of toluene and amine are thus recovered; 1081.6 g of acetylthiophene N-n-butylamine at 90% purity are obtained, namely a yield of 89.6%.

Provenance & Evidence