Hydrochloric Acid → HCID 53710796, compound

HRID 2049293Notes

Reaction equation

HRID 2049293 reaction equation
C[O:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([O:11][CH2:12][CH:13]=[C:14]([Cl:16])[CH3:15])=[CH:7][N:6]=1)=[O:4].Cl>>[Cl:16][C:14]([CH3:15])=[CH:13][CH2:12][O:11][C:8]1[CH:9]=[CH:10][C:5]([C:3]([OH:4])=[O:2])=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 53733984HCID 53733984, compound

Product 1

HCID 53710796HCID 53710796, compound

Procedure

A mixture of 3.0 g of 5-(3-chloro-2-butenyloxy)-2-pyridinecarboxylic acid methyl ester and 30 ml of 6 N-hydrochloric acid is heated on a steam bath for one hour. After that, the solution is cooled and the pH is adjusted to 5-6. Then the solution is evaporated and the residue extracted with ethanol. The ethanol extract is evaporated to yield 5-(3-chloro-2-butenyloxy)-2-pyridinecarboxylic acid melting at 96°-98°.

Workup

  1. temperatureis heated on a steam bath for one hour
  2. temperatureAfter that, the solution is cooled
  3. customThen the solution is evaporated
  4. extractionthe residue extracted with ethanol
  5. extractionThe ethanol extract
  6. customis evaporated

Sources & evidence

ORD record
ord-2b0972c1c4d94e9bbbcf2288953d11bf
Source dataset
uspto-grants-1980_04
Patent number
US04197302

Reaction notes

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