Dimethylamine → HCID 178484606, compound

Participants

Reaction Steps

Ethyl 5-mercapto-1H-tetrazol-1-ylacetate (1.5 g) in ethanol (10 ml) and 33% dimethylamine in ethanol (6 ml) were mixed and set aside for seven days. Further 33% dimethylamine in ethanol (6 ml) was added and the solution left for 7 more days then evaporated to dryness in vacuo. The residue was dissolved in water (50 ml), adjusted to pH 1.8, and concentrated to ca 20 ml in vacuo. The solution was cooled in ice and the crystalline product collected, 0.94 g (63.0%), m.p. 204°-205°; ε [(CD3)2CO] 3.02 and 3.28 (6H, 2×s --N(CH3)2), 5.35 (2H,s, --CH2CO--), 7.7 (1H,bs, --SH). Found: C, 32.21; H, 5.01; N, 37.63; S, 16.99. C5H9N5OS requires: C, 32.08; H, 4.85; N, 37.41; S, 17.13%.

Provenance & Evidence