HCID 20344096, compound → HCID 20344098, compound

HRID 2049629Notes

Reaction equation

HRID 2049629 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:17]=[CH:18][CH:19]=1)[O:5][C:6]1[CH:16]=[CH:15][CH:14]=[CH:13][C:7]=1[C:8](OCC)=[O:9].[H-].[Al+3].[Li+].[H-].[H-].[H-]>CCOCC>[F:1][C:2]1[CH:3]=[C:4]([CH:17]=[CH:18][CH:19]=1)[O:5][C:6]1[CH:16]=[CH:15][CH:14]=[CH:13][C:7]=1[CH2:8][OH:9]

Participants

4

Reactant 2

HCID 20344096HCID 20344096, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 20344098HCID 20344098, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Procedure

Ethyl 2-(3-fluorophenoxy)benzoate (37 g.) dissolved in 90 ml. of ether, was added dropwise to a suspension of lithium aluminum hydride (4.5 g.) in 350 ml of ether. The reaction mixture was heated to reflux for 6 hours to give, after work-up, 30 g. of the title compound. ##STR11##

Workup

  1. temperatureThe reaction mixture was heated
  2. temperatureto reflux for 6 hours
  3. customto give

Sources & evidence

ORD record
ord-53aadc8e99ea495b91c79fd82f8b881d
Source dataset
uspto-grants-1980_04
Patent number
US04198421

Reaction notes

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