Thiocyanic acid, chloromethyl ester → HCID 53691075, compound

HRID 2049670Notes

Reaction equation

HRID 2049670 reaction equation
[CH3:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[S:7])=[CH:4][CH:3]=1.Cl[CH2:12][S:13][C:14]#[N:15]>>[S:13]([CH2:12][O:8][C:6](=[S:7])[C:5]1[CH:9]=[CH:10][C:2]([CH3:1])=[CH:3][CH:4]=1)[C:14]#[N:15]

Participants

3

Reactant 2

HCID 76755Thiocyanic acid, chloromethyl esterHCID 1784259114-Methylthiobenzoic acid

Product 1

HCID 53691075HCID 53691075, compoundYield 80%

Procedure

20.5 g (0.11 mol) of the K salt of 4-methyl-thiobenzoic acid and 11.7 g (0.11 mol) of chloromethyl thiocyanate were reacted and processed as in Example 1 B. 22.5 g of a light powder resulted and, after recrystallisation from ligroin, 18 g of white crystals resulted; melting point 55° (this corresponds to a yield of 80% of the theoretical conversion).

Workup

  1. custom22.5 g of a light powder resulted
  2. customafter recrystallisation from ligroin, 18 g of white crystals
  3. customresulted

Sources & evidence

ORD record
ord-64c61d4a85004d3f84bae29f0ae93210
Source dataset
uspto-grants-1980_04
Patent number
US04198428

Reaction notes

Loading…