HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Iodide → HCID 20344057, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | Propargyl bromide | HCID 7842 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | HCID 20344046 | HCID 20344046 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 20344057 | HCID 20344057 | — |
Reaction Steps
A mixture of 2.5 g of 2-chloro-10,11-dihydro-11-oxospiro[dibenz(b,f)thiepin-10,4'-piperidine], free base of Example 5, 2.5 g of sodium bicarbonate, 2.0 g of potassium iodide and 1.1 g of propargyl bromide in 30 ml of dimethylformamide is treated according to the procedure of Example 16 to provide 2-chloro-10,11-dihydro-11-oxo-1'-(2-propynyl)spiro[dibenz(b,f)thiepin-10,4'-piperidine].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04198420 |
| Source dataset | uspto-grants-1980_04 |
| ORD ID | ord-1c2bd3dd15e543018864b4656f4e6dd6 |
| Source note | uspto-grants-1980_04 |