HCID 23466055, compound → HCID 12878322, compound

HRID 2049715Notes

Reaction equation

HRID 2049715 reaction equation
[OH:1][C:2]1([CH3:27])[CH2:8][CH:7]([CH2:9][CH2:10][C:11]2[CH:16]=[CH:15][C:14]([O:17]CC3C=CC=CC=3)=[C:13]([O:25][CH3:26])[CH:12]=2)[O:6][C:4](=[O:5])[CH2:3]1>[Pd].C(OCC)(=O)C>[OH:1][C:2]1([CH3:27])[CH2:8][CH:7]([CH2:9][CH2:10][C:11]2[CH:16]=[CH:15][C:14]([OH:17])=[C:13]([O:25][CH3:26])[CH:12]=2)[O:6][C:4](=[O:5])[CH2:3]1

Participants

4

Reactant 1

HCID 23466055HCID 23466055, compound

Product 1

HCID 12878322HCID 12878322, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

Using 140 mg of 3hydroxy-3-methyl-7-(p-benzyloxy-m-methoxyphenyl)-5-heptanolide, 140 mg of 5% palladium-charcoal and 14 ml of ethyl acetate, the reaction and the purification of the product were carried out according to the method described in Example 27 affording 75 mg of the desired compound melting at 162°-164° C.

Workup

  1. customthe reaction
  2. customthe purification of the product

Sources & evidence

ORD record
ord-b3788cde3a0b4905a80984e26e21a53a
Source dataset
uspto-grants-1980_04
Patent number
US04198425

Reaction notes

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