2-Chlorobenzyl chloride → HCID 12788616, compound

HRID 2049748Notes

Reaction equation

HRID 2049748 reaction equation
[C:1]([C:4]1[C:5]([N:16]([CH3:18])[CH3:17])=[C:6]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[NH:7][C:8]=1[CH3:9])(=[O:3])[CH3:2].[Cl:19][C:20]1[CH:27]=[CH:26][CH:25]=[CH:24][C:21]=1[CH2:22]Cl>C(O)(C)C>[C:1]([C:4]1[C:5]([N:16]([CH3:18])[CH3:17])=[C:6]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[N:7]([CH2:22][C:21]2[CH:24]=[CH:25][CH:26]=[CH:27][C:20]=2[Cl:19])[C:8]=1[CH3:9])(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 119062-Chlorobenzyl chlorideHCID 41889Ethanone, 1-(4-(dimethylamino)-2-methyl-5-phenyl-1H-pyrrol-3-yl)-

Product 1

HCID 12788616HCID 12788616, compoundYield 67%

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

The title compound is prepared in a 67% yield by starting from the compound of Example 43 and o-chlorobenzyl chloride, using procedure (a) of Example 49; m.p. 103°-5° C. (from isopropanol).

Sources & evidence

ORD record
ord-dbc22535ee334d1f8e0298af28196342
Source dataset
uspto-grants-1980_04
Patent number
US04198502

Reaction notes

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