反应详情

In 50 ml of toluene, 1.60 g of 4-pentenophenone, 2.13 g of pyrrolidine and 0.14 g of boron trifluoride etherate were dissolved. The mixture was refluxed for 46 hours using a Cope water separator and molecular sieve 4A as the dehydrating agent. After having distilled out the solvent under a reduced pressure, the residue was subjected to a distillation under a reduced pressure to obtain 1.68 g of the desired enamine (yield: 79%).

1. temperatureThe mixture was refluxed for 46 hours
2. distillationAfter having distilled out the solvent under a reduced pressure
3. distillationthe residue was subjected to a distillation under a reduced pressure