Methyl bromoacetate → HCID 20344441, compound

HRID 2049772Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][CH:9]([C:14]#[N:15])[C:10]([O:12][CH3:13])=[O:11].Br[CH2:17][C:18]([O:20][CH3:21])=[O:19]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([C:14]#[N:15])([C:10]([O:12][CH3:13])=[O:11])[CH2:17][C:18]([O:20][CH3:21])=[O:19]

Participants

Reactant 2

HCID 60984Methyl bromoacetate

HCID 275607methyl 3-(2-chlorophenyl)-2-cyanopropanoate

Product 1

HCID 20344441HCID 20344441, compound

Procedure

In the same manner as Example 1-(b), 100 g of methyl 3-(2-chlorophenyl)-2-cyanopropionate was reacted with methyl bromoacetate to obtain methyl 4-(2-chlorophenyl)-3-cyano-3-methoxycarbonylbutyrate.

Sources & evidence

ORD record: ord-9c84a60853f54b55a4651e4bd478f187
Source dataset: uspto-grants-1980_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04198514

Reaction notes

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