Methyl bromoacetate → HCID 20344433, compound
Reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH2:8][CH:9]([C:14]#[N:15])[C:10]([O:12][CH3:13])=[O:11])[CH:5]=[CH:6][CH:7]=1.Br[CH2:17][C:18]([O:20][CH3:21])=[O:19]>>[Cl:1][C:2]1[CH:3]=[C:4]([CH2:8][C:9]([C:14]#[N:15])([C:10]([O:12][CH3:13])=[O:11])[CH2:17][C:18]([O:20][CH3:21])=[O:19])[CH:5]=[CH:6][CH:7]=1Participants
3
Procedure
In the same manner as Example 1-(b), 26.5 g of methyl 3-(3-chlorophenyl)-2-cyanopropionate was reacted with methyl bromoacetate to obtain methyl 4-(3-chlorophenyl)-3-cyano-3-methoxycarbonylbutyrate.
Sources & evidence
- ORD record
- ord-69e8114c0f7844e682d89db514a737fc
- Source dataset
- uspto-grants-1980_04
- Patent number
- US04198514
Reaction notes
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