2,2,2-Trifluoroethanol → HCID 11469181, compound

Participants

Reaction Steps

In 100 ml DMF is placed 2,2,2-trifluoroethanol (20 g), 3-chloro-2-methyl-1-propene (18.1 g) and potassium carbonate (33.15 g). The mixture is heated to 50°, with stirring, for 15 hr. The solution is cooled and extracted with pentane. The pentane layer is washed with water (3X) and dried over sodium sulfate. The pentane is fractionally distilled off and the product is distilled in vacuo to give 2,2,2-trifluoroethyl 2-methyl-2-propenyl ether.

Provenance & Evidence