HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Sulfite → 3-(2-Sulfoethyl)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Sulfite | HCID 24437 | — |
| Reactant | 3-(2-Chloroethyl)pyridine | HCID 199466 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-(2-Sulfoethyl)pyridine | HCID 19377944 | — |
Reaction Steps
A mixture of Na2SO3 (2.7 g., 21 m.moles) and (3-(2-chloroethyl)pyridine (1.2 g., 8.5 m.moles) in water (10 ml.) was heated under reflux overnight with stirring and column chromatographed on IR-120 resin (H+, 100 ml.) by eluting with water. The eluate containing the desired product was collected and concentrated to give colorless plates (1.1 g., 69%), melting at 275°-278° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04198504 |
| Source dataset | uspto-grants-1980_04 |
| ORD ID | ord-8c9c0e803aa34585af97726551c66331 |
| Source note | uspto-grants-1980_04 |