Hydrochloric Acid → HCID 20343991, compound

HRID 2049871Notes

Reaction equation

HRID 2049871 reaction equation
[C:1]([C:4]1([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[S:18][C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH2:9][CH2:8][N:7](C#N)[CH2:6][CH2:5]1)(=[O:3])[CH3:2].[ClH:25]>>[ClH:25].[C:1]([C:4]1([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[S:18][C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH2:9][CH2:8][NH:7][CH2:6][CH2:5]1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 20343966HCID 20343966, compound

Product 1

HCID 20343991HCID 20343991, compound

Procedure

A solution of 4.8 g of 4-acetyl-1-cyano-4-(2-phenylthiophenyl)piperidine, Example 8, in 50 ml of 2 N hydrochloric acid is refluxed for 16 hours, effecting a white precipitate. The precipitate is collected by filtration and then washed twice with 50 ml portions of water and dried, providing 4-acetyl-4-(2-phenylthiophenyl)piperidine hydrochloride.

Workup

  1. filtrationThe precipitate is collected by filtration
  2. washwashed twice with 50 ml portions of water
  3. customdried

Sources & evidence

ORD record
ord-932ba553594a489fa8a57de8c6430ddf
Source dataset
uspto-grants-1980_04
Patent number
US04198419

Reaction notes

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