Potassium Carbonate → HCID 23452870, compound

HRID 2049912Notes

Reaction equation

HRID 2049912 reaction equation
[CH3:1][O:2][C:3](=[O:18])[C:4]1[CH:13]=[C:12]([OH:14])[CH:11]=[C:6]([C:7]([O:9][CH3:10])=[O:8])[C:5]=1[N+:15]([O-:17])=[O:16].C(=O)([O-])[O-].[K+].[K+].[C:25]([O:29][C:30](=[O:33])[CH2:31]Br)([CH3:28])([CH3:27])[CH3:26]>CC(C)=O>[C:25]([O:29][C:30](=[O:33])[CH2:31][O:14][C:12]1[CH:11]=[C:6]([C:7]([O:9][CH3:10])=[O:8])[C:5]([N+:15]([O-:17])=[O:16])=[C:4]([C:3]([O:2][CH3:1])=[O:18])[CH:13]=1)([CH3:28])([CH3:27])[CH3:26]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 79177tert-Butyl bromoacetateHCID 23452882HCID 23452882, compound

Product 1

HCID 23452870HCID 23452870, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To a solution of 2.55 g. of dimethyl-5-hydroxy-2-nitroisophthalate (prepared as in Example 15, Part B) in 25 ml. of acetone is added 0.69 g. of anhydrous potassium carbonate, followed by 1.95 g. of tert-butylbromoacetate. The mixture is stirred and refluxed for 20 hr. After this time, the cooled reaction mixture is poured with rapid stirring into 200 ml. of ice-cold 1% hydrochloric acid. The solid is collected and washed well with water. Yield 3.4 g.; m.p. 106°-108° C.

Workup

  1. temperaturerefluxed for 20 hr
  2. customAfter this time, the cooled reaction mixture
  3. additionis poured
  4. stirringwith rapid stirring into 200 ml
  5. customThe solid is collected
  6. washwashed well with water

Sources & evidence

ORD record
ord-7d78485eb975465da74a8491a541bbe9
Source dataset
uspto-grants-1980_04
Patent number
US04199354

Reaction notes

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