反应详情

To a well-stirred solution of 4.0 g (0.0160 mole) of the acid chloride of Example 16 in 20 ml. of ether was added dropwise 2.34 g (0.032 mole) of diethylamine in 5 ml. of ether. The insoluble salt was filtered. The ether solution was washed with water, dried and concentrated under reduced pressure. The residue was crystallized from hexane at low temperature to give 4.1 g of the desired product, m.p. 40°-41° C.

1. filtrationThe insoluble salt was filtered
2. washThe ether solution was washed with water
3. customdried
4. concentrationconcentrated under reduced pressure
5. customThe residue was crystallized from hexane at low temperature