Thionyl Chloride → HCID 20343343, compound

HRID 2050094Notes

Reaction equation

HRID 2050094 reaction equation
S(Cl)([Cl:3])=O.[F:5][C:6]([F:21])([F:20])[O:7][C:8]1[CH:19]=[CH:18][C:11]([CH:12](O)[C:13]([CH3:16])([CH3:15])[CH3:14])=[CH:10][CH:9]=1>>[Cl:3][CH:12]([C:11]1[CH:18]=[CH:19][C:8]([O:7][C:6]([F:21])([F:20])[F:5])=[CH:9][CH:10]=1)[C:13]([CH3:16])([CH3:15])[CH3:14]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 54195762HCID 54195762, compound

Product 1

HCID 20343343HCID 20343343, compound

Procedure

To freshly distilled thionyl chloride (14.87 g, 0.125 mol) cooled in salt ice bath is added in portions the neopentyl alcohol of Example 36 (12.4 g, 0.05 mol) over 30 minutes. The ice bath is removed and the slurry is left to stand overnight. Evaporation of excess thionyl chloride gives a solid.

Workup

  1. customThe ice bath is removed
  2. waitthe slurry is left
  3. customEvaporation of excess thionyl chloride
  4. customgives a solid

Sources & evidence

ORD record
ord-9375e2ad4f22470ba9f380f69b4a3658
Source dataset
uspto-grants-1980_04
Patent number
US04199595

Reaction notes

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