反应详情

In 3 liters of ethyl acetate and 50 ml of concentrated sulfuric acid were dissolved by heating 150 g of 2-amino-5-nitro-phenol and 350 g of octadecylsuccinate and the resulting solution was boiled under reflux for further 30 hours. Thereafter, the solution was cooled up to room temperature and washed twice with 2 liters of 10% hydrochloric acid and twice with 10% sodium carbonate solution. Then, ethyl acetated was distilled off and the residue was recrystallized from hexane to afford light yellow powdery crystal melting at 115°-120° C. in the yield of 153 g.

1. temperatureunder reflux for further 30 hours
2. washwashed twice with 2 liters of 10% hydrochloric acid and twice with 10% sodium carbonate solution
3. distillationThen, ethyl acetated was distilled off
4. customthe residue was recrystallized from hexane