HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propargylamine → 1-Cyano-2-(2-propynylamino)-2-{2-[(thiazol-2-yl)methylthio]ethylamino}ethylene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propargylamine | HCID 239041 | — |
| Reactant | 2-[(Thiazol-2-yl)methylthio]ethylamine | HCID 12923403 | — |
| Reactant | 3,3-Diethoxyacrylonitrile | HCID 15557848 | — |
| Reactant | 1-Cyano-2-ethoxy-2-propynylaminoethylene | HCID 86736951 | — |
| Product | 1-Cyano-2-(2-propynylamino)-2-{2-[(thiazol-2-yl)methylthio]ethylamino}ethylene | HCID 86736950 | — |
Reaction Steps
When 2-[(thiazol-2-yl)methylthio]ethylamine is reacted in an inert solvent with about an equimolar amount of 1-cyano-2-ethoxy-2-propynylaminoethylene [prepared from propargylamine and 1-cyano-2,2-bis(ethoxy)ethylene, which is itself prepared according to the procedure described in J. Am. Chem. Soc., 71, 47 (1949)], the title product is produced.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04200578 |
| Source dataset | uspto-grants-1980_04 |
| ORD ID | ord-fe468824072d4cdbac32aa0d22865c62 |
| Source note | uspto-grants-1980_04 |