HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propargylamine → 1-Cyano-2-(2-propynylamino)-2-{2-[(thiazol-2-yl)methylthio]ethylamino}ethylene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propargylamine | HCID 239041 | — |
| Reactant | 2-[(Thiazol-2-yl)methylthio]ethylamine | HCID 12923403 | — |
| Reactant | 3,3-Dimethoxyprop-2-enenitrile | HCID 22622700 | — |
| Reactant | 1-Cyano-2-methoxy-2-{2-[(thiazol-2-yl)methylthio]ethylamino}ethylene | HCID 70596681 | — |
| Product | 1-Cyano-2-(2-propynylamino)-2-{2-[(thiazol-2-yl)methylthio]ethylamino}ethylene | HCID 86736950 | — |
Reaction Steps
When 2-[(thiazol-2-yl)methylthio]ethylamine is reacted with 1-cyano-2,2-bis(methoxy)ethylene [prepared according to the procedure described in J. Chem. Soc., (Suppl. Issue No. 1), S106-111 (1949)] and the resultant 1-cyano-2-methoxy-2-{2-[(thiazol-2-yl)methylthio]ethylamino}ethylene is reacted with propargylamine in the procedure of Example 1, the title compound is produced.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04200578 |
| Source dataset | uspto-grants-1980_04 |
| ORD ID | ord-d796e6a1fb684cb68a7870d9a81f13d6 |
| Source note | uspto-grants-1980_04 |