Resorcinol → HCID 12713133, compound

HRID 2050337Notes

Reaction equation

HRID 2050337 reaction equation
[C:1]1([CH:8]=[CH:7][CH:6]=[C:4]([OH:5])[CH:3]=1)O.[CH2:9]([NH2:16])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[CH2:9]([NH:16][C:1]1[CH:3]=[C:4]([OH:5])[CH:6]=[CH:7][CH:8]=1)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

3

Reactant 2

HCID 5054ResorcinolHCID 7504Benzylamine

Product 1

HCID 12713133HCID 12713133, compound

Conditions

Temperature
5 °C

Procedure

Resorcinol (22 g) and 21.4 g of benzylamine were heated under an air condenser in a nitrogen atmosphere at 175°-185° C. for 5.5 hr. Then the air condenser was removed, and the temperature raised to 200°-203° where it was held for 1.5 hr. The red, viscous mass was cooled and boiled with 250 ml of 3:2 benzene-cyclohexane to form a solution. The solution was cooled several days at 5° C. to allow for the separation of oily material. The supernatant was decanted and evaporated to leave 12.0 g (30%) of pale-orange, viscous liquid 3-benzylaminophenol which was used without further purification.

Workup

  1. customThen the air condenser was removed
  2. temperaturethe temperature raised to 200°-203° where it
  3. temperatureThe red, viscous mass was cooled
  4. customto form a solution
  5. customto allow for the separation of oily material
  6. customThe supernatant was decanted
  7. customevaporated

Sources & evidence

ORD record
ord-1a049d605fba4c71a2951ac3cfa7ecd0
Source dataset
uspto-grants-1980_04
Patent number
US04200753

Reaction notes

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