HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Cyano-2,3-dimethylisothiourea → 1-Cyano-2-methyl-3-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)isothiourea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Cyano-2,3-dimethylisothiourea | HCID 111103 | — |
| Reactant | 4-(((2-Aminoethyl)thio)methyl)-5-methylimidazole | HCID 665568 | — |
| Product | 1-Cyano-2-methyl-3-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)isothiourea | HCID 103630 | — |
Reaction Steps
Furthermore, the final compound I can be obtained by reacting 4-[(2-aminoethyl)-thiomethyl]-5-methyl imidazole with N-cyano-N',S-dimethylisothiourea or with dimethylcyanodithioimido carbonate to form N-cyano-N'-{2-[(5-methylimidazole-4-yl)-methylthio]-ethyl}-S-methylisothiourea, which reacts with methylamine, thus yielding the final compound I.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04200761 |
| Source dataset | uspto-grants-1980_04 |
| ORD ID | ord-283a9fab509d42b290276d309c3385d8 |
| Source note | uspto-grants-1980_04 |