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HRID2050387

反应详情

EQUATION

反应方程式

HRID 2050387 的结构方程式

REACTANTS

反应物

5
结构：Cc1ccc(S(=O)(=O)O)cc1
HCID6101

4-Methylbenzenesulfonic acid

C7H8O3S

结构：[N-]=[N+]=[N-].[Na+]
HCID33557

未命名化合物

结构：[BH4-].[Na+]
HCID4311764

Sodium borohydride (Na(BH4))

H4BNa

结构：OCC1CCN1
HCID15251628

(Azetidin-2-yl)methanol

C4H9NO

结构：COC(=O)[C@@H]1NC(=O)[C@@H]1NC(=O)OC(C)(C)C
HCID70428372

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N[C@H]1C(=O)N[C@H]1CN=[N+]=[N-]
HCID86734331

未命名化合物

PROCEDURE

实验过程

Sodium borohydride reduction of methyl cis-3-t-butoxycarbonylamino-4-oxoazetidine-2-carboxylate as described in Preparation 3, followed by conversion of the 2-hydroxymethylazetidine product to the p-toluenesulfonate derivative, mp 160°-162°(d), and the reaction of the derivative with sodium azide as described in Preparation 4 gives the title compound.

WORKUP

后处理

  1. customas described in Preparation 4