Chlorokojic acid → HCID 88436748, compound

HRID 2050491Notes

Reaction equation

HRID 2050491 reaction equation
[CH:1]1[C:6](=[O:7])[C:5]([OH:8])=[CH:4][O:3][C:2]=1C[Cl:10].[CH3:11][S:12][C:13]1[CH:18]=[CH:17][N:16]=[CH:15][N:14]=1>>[ClH:10].[Cl-:10].[OH:8][C:5]1[C:6](=[O:7])[CH:1]=[C:2]([N+:16]2[CH:17]=[CH:18][C:13]([S:12][CH3:11])=[N:14][CH:15]=2)[O:3][CH:4]=1

Participants

3

Reactant 2

HCID 82051Chlorokojic acidHCID 53247714-(Methylthio)pyrimidine

Product 1

HCID 88436748HCID 88436748, compound

Procedure

Chlorokojic acid (5 mmol) and 4-methylthiopyrimidine (5 mmol) were stirred at 170° C. for 10 minutes. The mixture melted, turned black, resolidified and was triturated with acetone to give as a crude solid, 1-(5-hydroxypyran-4-on-2-yl)-4-methylthiopyrimidinium chloride hydrochloride salt; (DMSO-d6)/130° C., 2.80(s,3H); 5.79(s,2H); 6.65(s,1H); 8.08(s,1H); 8.15(q,1H); 9.05(q,1H); 9.65(s,1H).

Workup

  1. customwas triturated with acetone

Sources & evidence

ORD record
ord-ae39dfe8988b426b9e21d535b74beab1
Source dataset
uspto-grants-1991_05
Patent number
US05013730

Reaction notes

Loading…