HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanone, 1-(2,5-dichlorophenyl)- → 2',5'-Dichloro-3-dimethylaminoacrylophenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanone, 1-(2,5-dichlorophenyl)- | HCID 75587 | — |
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Product | 2',5'-Dichloro-3-dimethylaminoacrylophenone | HCID 2806206 | — |
Reaction Steps
A mixture of 31.0 g of 2',5'-dichloroacetophenone and 25 ml of N,N-dimethylformamide dimethyl acetal is heated on a steam bath for 6 hours, then evaporated to dryness in vacuo. The residue is slurried with hexane, filtered, and gives 35.3 g of 2', 5'-dichloro-3-dimethylaminoacrylophenone as orange crystals, mp 83-85° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05013737 |
| Source dataset | uspto-grants-1991_05 |
| ORD ID | ord-6a74682f6a8b4686aad3c6ad5e00ee90 |
| Source note | uspto-grants-1991_05 |