Water → HCID 10337897, compound

HRID 2050522Notes

Reaction equation

HRID 2050522 reaction equation
Cl[C:2]1[C:11]([C:12]#[N:13])=[C:10]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=[CH:9]2)[N:3]=1.[C:14]1([CH:20]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH2:21][NH2:22])[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.O>CN(C)C=O>[C:12]([C:11]1[C:2]([NH:22][CH2:21][CH:20]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)=[N:3][C:4]2[C:10]=1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=2)#[N:13]

Participants

5

Reactant 3

HCID 962WaterHCID 775752,2-DiphenylethylamineHCID 10261891HCID 10261891, compound

Product 1

HCID 10337897HCID 10337897, compoundYield 78.6%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

To a solution of 0.38 g (0.002 mol) of 2-chloro-3-cyano-1-azaazulene in 7 ml of dimethylformamide were added 0.43 g (0.0022 mol) of 2,2-diphenylethylamine. The reaction mixture was stirred at room temperature for 24 hours. The reaction mixture was poured into water with ice to allow precipitate to separate out. The precipitate was filtered and dried to give 0.55 g of title compoind (yield: 78.6%).

Workup

  1. customto separate out
  2. filtrationThe precipitate was filtered
  3. customdried
  4. customto give 0.55 g of title compoind (yield: 78.6%)

Sources & evidence

ORD record
ord-da836b6e535a4e23bd65db011ebd7442
Source dataset
uspto-grants-1991_05
Patent number
US05013736

Reaction notes

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