Sulfuric Acid → HCID 57324703, compound

Participants

Reaction Steps

A mixture of 12.6 g of 2-thienylaminoacetic acid, 300 ml of dimethoxyethane, 15 ml of sulphuric acid and 100 ml of isobutene is stirred at room temperature in an autoclave for 5 h and poured into a mixture composed of 800 ml of ether and 800 ml of 1N sodium hydroxide solution. The ethereal phase is separated off, and the aqueous phase is extracted twice more by shaking with 200 ml of ether each time. After drying of the ether phases over MgSO4 and evaporation of the solvent there remains a yellowish oily residue.

Provenance & Evidence