2-Methoxyethylamine → 5-(beta-methoxyethyL)amino-2-[beta-(2-hydroxyethoxy)ethoxy]-4-nitrophenol

HRID 2051045Notes

Reaction equation

HRID 2051045 reaction equation
[N+:1]([C:4]1[C:9]([N+:10]([O-])=O)=[CH:8][C:7]([OH:13])=[C:6]([O:14][CH2:15][CH2:16][O:17][CH2:18][CH2:19][OH:20])[CH:5]=1)([O-:3])=[O:2].[CH3:21][O:22][CH2:23][CH2:24]N>O>[CH3:21][O:22][CH2:23][CH2:24][NH:10][C:9]1[C:4]([N+:1]([O-:3])=[O:2])=[CH:5][C:6]([O:14][CH2:15][CH2:16][O:17][CH2:18][CH2:19][OH:20])=[C:7]([OH:13])[CH:8]=1

Participants

4

Reactant 2

HCID 80182-MethoxyethylamineHCID 137508624,5-Dinitro-2-[beta-(2-hydroxyethoxy)ethoxy]phenol

Product 1

HCID 137508685-(beta-methoxyethyL)amino-2-[beta-(2-hydroxyethoxy)ethoxy]-4-nitrophenol

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture prepared by adding 0.07 mol (20.2 g) of 4,5-dinitro-2-[β-(2-hydroxyethoxy)ethoxy]phenol, prepared according to Example 4, to 0.28 mol (21 g) of 2-methoxyethylamine and 15 ml of water is heated under reflux.

Workup

  1. customA mixture prepared
  2. customprepared
  3. temperatureis heated
  4. temperatureunder reflux

Sources & evidence

ORD record
ord-d39b4b8ddb9642779aef3d8c1c38ad46
Source dataset
uspto-grants-1991_05
Patent number
US05015769

Reaction notes

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