Acetophenone → Dibenzoylmethane

HRID 2051049Notes

Reaction equation

HRID 2051049 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)(=[O:3])[CH3:2].[CH3:10][O-:11].[Na+]>C1(C)C(C)=CC=CC=1>[C:1]([CH2:2][C:10](=[O:11])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)(=[O:3])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

Participants

4

Reactant 2

HCID 7410AcetophenoneHCID 10942334Sodium Methoxide

Product 1

HCID 8433DibenzoylmethaneYield 193.4%

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

acetophenone (30.0 grams; 0.25 mol); sodium methoxide (17.3 grames; 0.3 mol) and xylene 28.,0 grams) were added to the resulting mixture (347.0 grams) from the azetropic distillation. The reaction procedure set forth hereinabove was repeated with this reaction mixture giving dibenzoylmethane (54.2 grams; 92% yield) 92% pure by GLC analysis.

Workup

  1. customThe reaction procedure

Sources & evidence

ORD record
ord-eb5e70a7695f4052b44cc506f81f4f70
Source dataset
uspto-grants-1991_05
Patent number
US05015777

Reaction notes

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