HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → 1H-Indole-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 1H-indole-2-carbonyl Chloride | HCID 11816208 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1H-Indole-2-carboxamide | HCID 594832 | — |
Reaction Steps
Indolyl carboxylic acid amides as starting materials may be produced by reacting an indolyl carboxylic acid chloride in absolute methylene chloride with an amine in the presence of pyridine at -10° to 0°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05017582 |
| Source dataset | uspto-grants-1991_05 |
| ORD ID | ord-1bb07629c5c440e796036d2c0ac6d1b6 |
| Source note | uspto-grants-1991_05 |