HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-chloro-3-nitro-beta-oxobenzenepropanoate → 1-(2-Chloro-3-nitrophenyl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-chloro-3-nitro-beta-oxobenzenepropanoate | HCID 15735718 | — |
| Reactant | Trifluoroacetic acid water | HCID 22392675 | — |
| Product | 1-(2-Chloro-3-nitrophenyl)ethanone | HCID 12463885 | 87.6% |
Reaction Steps
According to the procedure of Example 2, ethyl 2-chloro-3-nitro-β-oxobenzenepropanoate (14.0 g, 51.5 mmol) is reacted with 30% water/trifluoroacetic acid to give 1-(2-chloro-3-nitrophenyl)ethanone (9.0 g, 87%), mp=41-43° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05017604 |
| Source dataset | uspto-grants-1991_05 |
| ORD ID | ord-1146b14d05d44b9e9ff59fa053e043b5 |
| Source note | uspto-grants-1991_05 |