HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tyramine → HCID 54459467, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tyramine | HCID 5610 | — |
| Reactant | (R)-(+)-3-Chlorostyrene oxide | HCID 10898919 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 54459467 | HCID 54459467 | — |
Reaction Steps
Thus, for the preparation of the amine starting material in Example 11 hereinafter, tyramine was reacted with (R)-m-chloro-styrene oxide in DMSO while heating to give (R)-m-chloro-[[(p-hydroxyphenethyl)amino]methyl]benzyl alcohol and the latter was etherified by reaction with 2-ethoxyethylmethanesulphonate to give (R)-m-chloro-α-[[[(p-(2 -ethoxyethoxy)phenethyl]amino]methyl]benzyl alcohol, [α]20/D=-20° (c=0.5 in methanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05017619 |
| Source dataset | uspto-grants-1991_05 |
| ORD ID | ord-83f59cfc1faf408eb49a781b0789d93b |
| Source note | uspto-grants-1991_05 |